Pamidronate and Osteonecrosis of the Jaw

FYI, we have identified a probable case of osteonecrosis, brought on by tooth extraction in a HD patient who had been receiving 90mg of Pamidronate IV for 30 months. This just discovered two days before Health Canada issued an alert! I'll do a literature search and put it in the Renal Pharmacist. There is no safety data on using long-term Pamidronate in the HD population. Let me know if you have had any adverse events in your HD population please.
THnaks
Lisa
l.sever@aci.on.ca